The analysis of the 31 statistically significant DEGs from the GSE99039 database revealed, as expected, the regulation of several broad inflammatory pathways, including “Th1, Th2, and Th17 differentiation”, “JAK-STAT signaling”, and “cytokine–cytokine receptor interaction.” Interestingly, we also observed enrichment in pathways typically associated with nervous tissue—such as “neurodegeneration”, “Alzheimer’s disease”, and “neuroactive ligand–receptor interaction”—within leukocytes. The gene discussed is SOAT1; the disease is early-onset autosomal dominant Alzheimer disease.