PPARG and breast cancer: The cytotoxic potential against breast cancer cells (MCF-7 cells, IC50 of 10 μM) as well as the PPAR-γ activating potential have also been reported for 5β,19-epoxy-19-methoxycucurbita-6,23-dien-3β,25-diol, another triterpenoid compound isolated from the plant [26].