Besides the plant’s key bioactive compounds like cucurbitane-type triterpenoids and alpha-momorcharin (α-MMC), which have reportedly shown significant cytotoxic, antitumor, and immunomodulatory properties, other compounds, such as α-spinasterol, stigmasterol, campesterol, and stigmasta-7,25-dien-3beta-ol, have also displayed non-toxic and drug-like properties [16], while the triterpenoid, 5β,19-epoxy-19-methoxycucurbita-6,23-dien-3β,25-diol has also been identified as a peroxisome proliferator-activated receptor-γ (PPAR-γ) activator in breast cancer MCF-7 cells [17]. Here, PPARG is linked to breast cancer.