FOXP3 and myeloid sarcoma: The mRNA expression and release of inflammatory mediators [IL-6, IL-1β, IFN-γ (interferon γ), TNF-α, CCL2 (C-C motif ligand 2) and CXCL8 (CXC motif ligand 8)] was significantly decreased, whether the expression of sirtuin-1 and scurfin (Foxp3) was increased, mitigating the elevated expression of pro-inflammatory cytokines that promote MS pathogenesis.