MUC1 and esophageal cancer: For instance, MUC1, which is overexpressed in the colon, breast, lung, pancreatic, bladder, ovarian, bladder, gastric, and esophageal cancer [228,229,230,231,232,233,234], has been reported as a critical protein for the development of pluripotency, platform proteins secreted by tumor-associated surface proteases [58,235].