MUC1 and breast cancer: More specifically, the overexpression of MUC1 in pancreatic and breast cancer cells interacts with signaling pathways, such as the MAPK, JAK/STAT, and the PI3K/AKT/mTOR pathways, and VEGF co-receptor, neuropilin-1, to promote the generation of endothelial cell and ectopic blood vessels [144,180].