Also, when extracts and cisplatin were administered to prostate cancer cells, the mRNA expression of Bax and p53 increased, while that of Kallikrein-2 (KLK2), nanog homeobox (NANOG), transforming growth factor (TGF), BCL-2, and TNF-α decreased [84]. The gene discussed is KLK2; the disease is Familial prostate cancer.