In contrast to the studies described above, the findings of Ahmad et al. [102] suggest an association between elevated gal-3 concentrations and reduced physical performance in patients with HF, where elevated gal-3 concentrations were inversely correlated with the results of the short physical performance battery (r2 = 0.089, p < 0.05) and handgrip strength (r2 = 0.078, p < 0.05). Here, LGALS3 is linked to hydrops fetalis.