For anemia, the main pathways included pathways in cancer, lipid, and atherosclerosis, AGE-RAGE signaling pathway in diabetic complications, EGFR tyrosine kinase inhibitor resistance, HIF-1 signaling pathway, prostate cancer, hepatitis B, Kaposi sarcoma-associated herpesvirus infection, central carbon metabolism in cancer, and viral carcinogenesis (Figure 4D). The gene discussed is EGFR; the disease is hepatitis B virus infection.