In glioma, the circular RNA of exon-encoded origin by Nei Like DNA Glycosylase 3 (circNEIL3) is packaged into exosomes by hnRNPA2B1 and transmitted to infiltrated tumor-associated macrophages, conferring the immunosuppressive ability, which will support and promote tumor progression [46,47]. This evidence concerns the gene HNRNPA2B1 and neoplasm.