Findings about Nectin-2 expression in lung adenocarcinoma suggest that it may be a potential target for immunotherapy [22], and tumors located in the right colon were found to have a higher likelihood of expressing Nectin-2, along with other Nectins, compared to those in the left colon, highlighting the potential prognostic value of Nectins in colorectal cancer [23]. This evidence concerns the gene NECTIN2 and colorectal cancer.