FNIP1 and cystic kidney disease: Further analyses of Fnip1-deficient mice have revealed a multitude of other phenotypes, including defective invariant NKT cell development [28], hypertrophic cardiomyopathy [29], fiber type switch and altered mitochondrial dynamics in skeletal muscle [30], muscle-dysfunction-related bone loss [19], increased adipose tissue browning [31], and renal cyst formation [32].