Studies have shown that polysaccharides from I. obliquus reduce the release of pro-inflammatory cytokines in body cells by inhibiting the TLR4/NF-κB signaling pathway, thereby alleviating symptoms of endometritis induced by lipopolysaccharides (LPSs), and can serve as an effective drug for the prevention and treatment of LPS-induced endometritis. This evidence concerns the gene NFKB1 and endometritis.