TEAD1 and colorectal carcinoma: Wang et al. demonstrated that KDM3A depletion led to the upregulation of H3K9me2 at TEA domain transcription factor 1 (TEAD1)-binding enhancers, which further resulted in decreased H3K27ac (acetylation), reduced TEAD1 binding to the enhancer, and impaired growth and migration of CRC cells [118].