Chen et al. reported that the zinc finger CCHC domain-containing protein 4 (a m6A methyltransferase)–lncRNA GHRLOS-KDM5D axis regulated CRC progression in vitro and in vivo, and that KDM5D overexpression impaired CRC cell proliferation, migration, and invasion [156]. This evidence concerns the gene GHRLOS and colorectal carcinoma.