We found that GDF6 expression was significantly correlated with immune infiltration in 28 types of cancer, with 22 showing a positive correlation, such as BRCA, LUAD, ESCA, STES, KIPAN, COAD, COADREAD, PRAD, STAD, HNSC, KIRC, LIHC, TARGET-WT, SKCM, BLCA, SKCM-M, READ, OV, UVM, PAAD, PCPG, and CHOL, and 6 showing a negative correlation, including GBMLGG, LGG, UCEC, TGCT, LAML, and TARGET -ALL-R (Figure 4A). This evidence concerns the gene GDF6 and cancer.