SEZ6 and neoplasm: Ten of 11 cases (91%) were positive for both DLL3 and SEZ6 (Fig. 3), with staining intensities ranging from weak to strong in 20–100% of tumor cells for DLL3 (average H-score 199, range 50–300), and with moderate to strong staining intensities in 40–100% of cells for SEZ6 (average H-score 224, range 120–300).