Other genetic variants associated with nephrotic syndrome also impair podocyte endocytosis, such as clavesin‐1 (CLVS1), which affects clathrin‐mediated endocytosis [487], or GAPVD1 (GTPase activating protein and VPS9 domains 1) and ANKFY1 (ankyrin repeat and FYVE domain‐containing protein 1) which interact with the endosomal regulator ras‐related protein rab5 [488]. This evidence concerns the gene GAPVD1 and nephrotic syndrome.