GLP1R and type 2 diabetes mellitus: This is particularly beneficial for diabetesmanagement as it reduces the risk of hypoglycemiaa commonside effect of several antidiabetes drugs, including insulin. Additionally, GLP-1 demonstrates positive effectson multiple tissues and organs, with the widespread presence of GLP-1Rsuggesting that GLP-1 plays broader roles beyond glucose metabolism.Significant efforts were made to develop GLP-1 as a therapeutic drugafter researchers observed that intravenous injections of GLP-1 hadbeneficial effects on insulin secretion and blood glucose controlin patients with type 2 diabetes.