Within COVID-19+, robust increases in the percentages of IFN-γ+CD4+TRM and IFN-γ+CD8+TRM in response to S peptide (8- and 50-fold, respectively, compared to 0 in controls) were noted only in subject #10 (female COVID-19+ with the shortest convalescence vaccinated at 27 days before tissue resection) (Figure 3P,Q). This evidence concerns the gene CD4 and COVID-19.