Additionally, tumor of poor differentiation (HR=4.735, 95% CI 1.312-17.088, P=0.018) and arterial invasion (HR=2.324, 95% CI 1.166-4.633, P=0.017) were associated with worse survival, while anti-PD1 therapy (HR=0.497, 95% CI 0.269–0.917, P=0.025) was likely to prolong OS (Supplementary Table S2). Here, PDCD1 is linked to neoplasm.