SAVI is a systemic inflammatory disease distinguished by specific laboratory markers, including elevated CRP and ESR levels, hyperimmunoglobulinemia marked by increased IgG and IgA levels, and the existence of various positive autoantibodies, such as ANA, ANCA, antiphospholipid antibodies, lupus anticoagulants, and anti-double-stranded DNA antibodies. The gene discussed is CRP; the disease is STING-associated vasculopathy with onset in infancy.