Drug-induced renal failure accounts for approximately 25% of acute kidney injury (AKI) cases in hospitalized patients, with aminoglycoside antibiotics, NSAIDs, contrast agents, and angiotensin-converting enzyme inhibitors (ACEi) among the most common causative drugs (Ghane Shahrbaf and Assadi, 2015; Gong et al., 2022). This evidence concerns the gene ACE and acute kidney injury.