KLF5 and hepatocellular carcinoma: According to the reported literature,2 the roles of KLFs in HCC can be divided into four categories: promoting (KLF5, KLF7, KLF8, and KLF15), inhibiting (KLF2, KLF3, KLF9 ∼ KLF12, and KLF17), dual (KLF4 and KLF6), and unknown (KLF1, KLF13, KLF14, and KLF16) functions.