Since A549 Is a p53 wild-type cell line and Huh7 harbors a p53 mutation, we also included H1299 (p53-null) for lung cancer and HepG2 (p53 wild-type) for liver cancer to investigate whether the treatment effect of P. chinensis extends to cancer cell lines with different p53 mutation statuses. This evidence concerns the gene TP53 and lung carcinoma.