The results showed that the levels of CRP (42.92 ± 51.94 vs.2.73 ± 4.93, P<0.001), ESR (64.49 ± 32.20 vs.19.96 ± 15.30, P<0.001), and FIB (4.85 ± 1.65 vs.3.16 ± 2.06, P<0.001) were significantly higher in the PJI group than in the AL group. The gene discussed is CRP; the disease is juvenile polyposis syndrome.