For example, DHA’s ability to reverse EMT markers (e.g., upregulation of E-Cadherin and downregulation of N-Cadherin, MMP-2, and MMP-9) suggests its potential to prevent tumor spread, a major challenge in NSCLC treatment (Kalia, 2015; Davis et al., 2014). This evidence concerns the gene CDH2 and non-small cell lung carcinoma.