Although this study primarily focused on reports of GLP-1 RA-induced cholecystitis and cholelithiasis, we also applied the shrinkage measure method to analyze 147 concomitant medications used alongside GLP-1 RAs for signal detection (Noguchi et al., 2020a; Noguchi et al., 2020b). The gene discussed is GLP1R; the disease is cholelithiasis.