Simultaneously, PRC1 was found to be linked to TGF-β-induced epithelial-mesenchymal transition-related lung and pancreatic cancer cell lines (Wanna-Udom et al., 2021); CDKN3 has a role in regulating proliferation, invasion, and EMT transition in nasopharyngeal and lung cancers (Wang et al., 2011; Xing et al., 2012; Gao et al., 2019); TNS4 was reported to be associated with regulation of cell adhesion, motility, invasion and EMT in colorectal cancer (Raposo et al., 2020). This evidence concerns the gene TGFB1 and colorectal cancer.