The genotypes of four variants in the IL2/IL21 region (rs13151961, rs13119723, rs6822844, and rs6840978) and 10 IL23R SNPs (rs1004819, rs10889677, rs11209032, rs2201841, and rs1495965) (Increased IBD susceptibility); rs7517847, rs10489629, rs11465804, rs11209026, and rs1343151 (decreased IBD susceptibility) were genotyped. This evidence concerns the gene IL2 and inflammatory bowel disease.