SMAD2 and pemphigus foliaceus: miR-101 has also shown to inhibit NFATc2 signal transduction by targeting Frizzled receptor 4 × 6, inhibiting WNT5a-induced PF proliferation, and inhibiting TGF-β–induced PF activation by targeting TGF-β1 receptor inhibition of SMAD2/3 signal transduction [106].