Recombinant adenovirus AdSurp-Hsp70 encoding the Hsp70 gene under the regulation of Survivin promoter demonstrated selective replication and lysis of survivin-positive gastric cancer cells and inhibition of tumor growth inhibited tumor growth of gastric cancer xenografts in immunodeficient and immune-reconstructed mouse models (53). The gene discussed is BIRC5; the disease is neoplasm.