CALR and sialadenitis: In 2016, the American College of Rheumatology (ACR) and the European League Against Rheumatism (EULAR) jointly designed and clinically validated consensus SjD classification methodology for patients with oral or ocular dryness that uses a combination of weighted factors, including the presence of anti-SSA/Ro autoantibodies in blood serum, a positive biopsy showing lymphocytic infiltration of the minor salivary glands (i.e., sialadenitis), and quantitative measurements of ocular staining, saliva flow rate and tear production (1).