MYOM2 and diffuse large B-cell lymphoma: The presence of M-protein has been significantly associated with very poor overall survival (OS) and progression-free survival (PFS) in patients with extranodal diffuse large B-cell lymphoma (DLBCL).[8] Clinical data from Chinese patients diagnosed with DLBCL revealed that chromosome abnormalities were detected in 31 of 88 patients (35.2%), with 15 of these patients (17.0%) showing a complex karyotype.