For example, studies have demonstrated that circRNA exosomal membrane protein 1 of EVs in patient serum samples can serve as a novel biomarker for non-small cell lung cancer, and it promotes non-small cell lung cancer proliferation by regulating the miR-524-5p-METTL3/SOX2 axis. The gene discussed is METTL3; the disease is non-small cell lung carcinoma.