All of these 6 genes have been previously identified as ferroptosis-related genes, among which BRD4 and FLT3 were found to be biomarkers in BC.[14,26] Our data revealed that BRD4, FLT3, and SIAH2 were the protective factors while CS, EMC2, and PIK3CA were the detrimental factors for BC patients. This evidence concerns the gene BRD4 and breast cancer.