Wu et al compared the onset of ICI-T1DM across ICI types (anti-PD-1, anti-programmed cell death ligand 1 [PD-L1]), or combination therapy, including anti-PD-1/anti-PD-L1 with anti-cytotoxic T-lymphocyte activating factor 4, and found no significant association (P = .780, F = 0.25).[7]. Here, CD274 is linked to type 1 diabetes mellitus.