The widespread presence of angiotensin converting enzyme 2 (ACE2) receptors in tissues explains 1 mechanism by which COVID-19 is able to impact such a wide variety of areas,[1] with a tendency to attack tissues that were already previously weak or held preexisting inflammation.[2] In addition, high levels of ACE2 are found in keratinocytes and basil cells, indicating a possible route of susceptibility in skin tissue.[3] A significant proportion of COVID-19 survivors continue to have symptoms that persist months after the acute phase of the disease. Here, ACE2 is linked to COVID-19.