Our analysis of the AD dataset GSE153760 identified 9 distinct cell types, as shown in Figure 4A. The specific expression markers for each cell type are presented in Figure 4B. Notably, proteins such as CACYBP, MOCS2, PSTPIP2, TNFAIP8, and TNIP1 were found to be expressed across various skin cells but exhibited heightened levels in immune cells, including T cells, monocytes, macrophages, and mast cells. This evidence concerns the gene TNIP1 and Alzheimer disease.