While the former is commonly found in IAS patients with IAAs, which lead to mild postprandial hyperglycemia and nocturnal hypoglycemia, whereas the latter (high-affinity/low-capacity antibodies) is associated with EIAS, which is typically accompanied by severe insulin resistance.[11] Probably, our case may have high-affinity/low-capacity antibodies to exogenous insulin. The gene discussed is INS; the disease is Insulin resistance.