HIF1A and neoplasm: In addition to the effect of lactate, DC glycolysis can promote tumor growth through some other related pathways: DC glycolysis can be reprogrammed by HIF-1, and in a recent study, it was found that CCR7 chemokines activate the HIF-1α transcription factor pathway in DC, and depending on this pathway, DC can undergo glycolytic reprogramming and migrate for antigen presentation.