To further investigate the effects of FD on inflammation, we examined the gene expression of endothelial cell adhesion molecules, platelet endothelial cell adhesion molecule-1 (PECAM-1), vascular endothelial cadherin (VE-cadherin), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) in hCMEC/D3 cells. The gene discussed is ESAM; the disease is Fabry disease.