UOX and gout: The present investigation demonstrated that treatment with QZTBD, but not BBR, attenuated dysbiosis of butyrate-producing bacteria in Uox-KO mice, including Akkermansia, Eubacterium, Ruminococcus, Butyricicoccus, Roseburia, Lactobacillus, Alistipes, Alloprevotella, and Bacteroides, highlighting the prebiotic potential of Chinese herbal medicines in the management of gouty arthritis.