In the PRAT-to-RSAT comparison, several genes, such as LSP1 (lymphocyte-specific protein 1), IRF1 (interferon regulatory factor 1), COTL1 (coactosin-like protein 1), BIRC3 (baculoviral inhibitor of apoptosis repeat-containing protein 3), and BCL2A1 (B-cell lymphoma 2 related protein A1), were positively correlated with insulin resistance markers (glucose, insulin, HOMA-IR), and body composition (fat mass %) (Fig. 4E). The gene discussed is INS; the disease is Insulin resistance.