DPYSL3 and Insulin resistance: Similarly, in the PRAT-to-OAT comparison, genes such as IRF1 (interferon regulatory factor 1), FNDC1 (fibronectin type III domain-containing protein 1), DPYSL3 (dihydropyrimidinase-like protein 3), and CD44 (cluster of differentiation 44) were positively correlated with markers of insulin resistance (glucose, insulin, and HOMA-IR) (Fig. 4F).