The logistic regression algorithm identified 8 genes (VDAC1, HSPA8, SOD1, HSPA9, TXN, NDUFS3, HSP90AB1, SNCA), among which 6 genes were closely correlated with the onset of sepsis-induced ALI (S7 Table, p < 0.05). Here, HSPA8 is linked to acute respiratory distress syndrome.