CD4 and Sepsis: As shown in Fig 7A and B, naive B cells, plasma cells, resting memory CD4 + T cells, activated memory CD4 + T cells, follicular helper T cells, macrophages M1, resting dendritic cells, activated mast cells, eosinophils were significantly reduced in sepsis-induced ALI samples, and naive CD4 + T cells, Monocytes, macrophages.M0, and Neutrophils were increased.