So it will be interesting to compare the ability of transgenes encoding other MYC proteins, such as NMYC and LMYC, as well as other oncoproteins (both those implicated and not implicated in human SCLC carcinogenesis) to convert RP cells into malignant tumors and to produce metastatic phenotypes, as we have observed here with RPM cells. The gene discussed is MYC; the disease is cancer.