To investigate the consequences of the observed enhanced cGAS-STING-IFN-I induction in APCs present in the TME of FXa-PAR2 signaling–deficient mice, we characterized the phenotypes of CD8+ T cells by generating scRNA-seq profiles of tumor-infiltrating lymphocytes from the TME of PyMT transgenic mice. Here, F2RL1 is linked to neoplasm.