64‐year‐old cachectic female with a remote history of colon cancer, poor performance status (ECOG = 2), uncontrolled HTN, and COPD on 2 L supplemental O2 presented with an unexpected weight loss of 20 lbs over the last 6 weeks (BMI = 17; serum albumin 2.2 g/dL), with anorexia and fatigue. This evidence concerns the gene ALB and malignant colon neoplasm.