109 (GIST or gastrointestinal stromal* or sarcoma* or melanoma* or breast* or meningioma* or tuberculos* or pancrea* or bile duct* or periampullary* or neuroendocrine* or prostat* or gallbladder* or ACTH or gastrinoma* or cholangiocarcinoma* tuberculos* or thyroid* or bladder* or renal or testicular or seminoma* or (lung adj3 (cancer or carcinoma*)) or colon* or ovar* or reirradiat* or second‐line* or second line* or reflux* or PPI or proton‐pump* or pump inhibitor or gastric‐acid* or acid* or re‐irradiat*).ti,kf. The gene discussed is POMC; the disease is sarcoma.