APOE and endometriosis: Additionally, Apolipoprotein E (APOE), a key protein in lipid metabolism reported to be elevated in aging and endometriosis ovaries[48, 49] and associated with reduced mature oocyte retrieval in older women,[50] was identified as a DEG primarily in the corpus luteum, atretic follicles, and mesenchymal cells of iron‐overloaded ovaries (Figure 7I–K).