PRC1 and breast cancer: The therapeutic potential of MSC-derived exosomes has been further supported by the work of Jia and Cai et al.,229,231 which showed that exosomal miR-9–3p and miR-139–5p, respectively, suppressed BC cell proliferation and migration by targeting key molecules like ESM1 and PRC1 that are critical for tumor cell survival and metastasis.