Research has shown that H3K18la upregulates the m6A reader protein YTH N6‐methyladenosine RNA binding protein 2 (YTHDF2), accelerating the degradation of period circadian regulator 1 (PER1) and tumor protein p53 (TP53) mRNAs and promoting malignancy in ocular melanoma [53]. This evidence concerns the gene PER1 and ocular melanoma.