Additionally, it has been reported that resveratrol fosters the survival of GC in PCOS rats by activating the PI3K/Akt/mammalian target of rapamycin (mTOR) signaling pathway, which reduce the expression of intracellular autophagy-related proteins light chain 3I (LC3I), LC3II, and Beclin-1, suppressing the formation of autophagosomes (106, 112). This evidence concerns the gene BECN1 and polycystic ovary syndrome.