We next investigated the role of Tbet in TME BM Treg cells using the MLL-AF9 leukemic model with adoptive transfer of 20% of 3 types of Treg cells: WT (ST2+) versus Tbet−/− versus ST2−/− Treg cells and compared it to the no tumor model (Fig. 7A). Here, IL1RL1 is linked to neoplasm.