CD8A and neoplasm: Since antigen-specific central memory T cells provide a better antitumoral immunity compared to effector memory T cells due to their ability to rapidly recirculate through secondary lymphoid organs, allowing for sustained antigen presentation and a more robust immune response against cancer cells when re-exposed to tumor antigens39, we explored the frequency of central memory CD8 T cells within WT1-tetramer+ CD8 T cells.